HCSGD entry for TUBA1C
1. General information
| Official gene symbol | TUBA1C |
|---|---|
| Entrez ID | 84790 |
| Gene full name | tubulin, alpha 1c |
| Other gene symbols | TUBA6 bcm948 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005198 | Structural molecule activity | TAS | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA TAS | cellular_component |
| GO:0005881 | Cytoplasmic microtubule | IEA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0007017 | Microtubule-based process | IEA TAS | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0030705 | Cytoskeleton-dependent intracellular transport | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
| GO:0051258 | Protein polymerization | IEA | biological_process |
| GO:0051301 | Cell division | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9801895065 | 0.0225238061 | 0.9999902473 | 0.2889127618 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0862020103 |
| GSE13712_SHEAR | Down | -0.0092249066 |
| GSE13712_STATIC | Down | -0.0790414355 |
| GSE19018 | Down | -0.0718693618 |
| GSE19899_A1 | Down | -0.3546658384 |
| GSE19899_A2 | Down | -0.4168294572 |
| PubMed_21979375_A1 | Down | -0.3707310902 |
| PubMed_21979375_A2 | Down | -0.4493474981 |
| GSE35957 | Down | -0.6789303969 |
| GSE36640 | Down | -0.2842060082 |
| GSE54402 | Up | 0.0029224136 |
| GSE9593 | Down | -0.3502738580 |
| GSE43922 | Down | -0.2868945700 |
| GSE24585 | Up | 0.0956858030 |
| GSE37065 | Down | -0.2786021400 |
| GSE28863_A1 | Down | -0.0699538864 |
| GSE28863_A2 | Down | -0.0013493491 |
| GSE28863_A3 | Down | -0.5473671559 |
| GSE28863_A4 | Up | 0.2335156498 |
| GSE48662 | Down | -1.0808471069 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Epothilone D | DB01873 | EXPT01350 |
| Epothilone B | DB03010 | EXPT01349 |
| CYT997 | DB05147 | - |
| 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE | DB07574 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031663 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-940 | MIMAT0004983 | MIRT036595 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036769 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036933 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038397 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043045 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046865 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049110 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052239 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
