HCSGD entry for CBX2
1. General information
| Official gene symbol | CBX2 |
|---|---|
| Entrez ID | 84733 |
| Gene full name | chromobox homolog 2 |
| Other gene symbols | CDCA6 M33 SRXY5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0000792 | Heterochromatin | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0031519 | PcG protein complex | IDA | cellular_component |
| GO:0035064 | Methylated histone residue binding | IEA | molecular_function |
| GO:0035102 | PRC1 complex | IDA | cellular_component |
| GO:0045137 | Development of primary sexual characteristics | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8919176133 | 0.4274661829 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1017792200 |
| GSE13712_SHEAR | Down | -0.3129566774 |
| GSE13712_STATIC | Up | 0.0243989130 |
| GSE19018 | Up | 0.0006040365 |
| GSE19899_A1 | Down | -0.0097638142 |
| GSE19899_A2 | Up | 0.0717166010 |
| PubMed_21979375_A1 | Up | 0.1868702896 |
| PubMed_21979375_A2 | Down | -0.0820435328 |
| GSE35957 | Down | -0.0106631484 |
| GSE36640 | Down | -0.5032058365 |
| GSE54402 | Up | 0.1018443070 |
| GSE9593 | Down | -0.0732642940 |
| GSE43922 | Up | 0.1388402027 |
| GSE24585 | Down | -0.1244437471 |
| GSE37065 | Down | -0.0451591971 |
| GSE28863_A1 | Down | -0.1530195801 |
| GSE28863_A2 | Down | -0.0703720134 |
| GSE28863_A3 | Up | 0.2635239611 |
| GSE28863_A4 | Up | 0.0547753646 |
| GSE48662 | Down | -0.1504274795 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023121 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT024030 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045012 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046777 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049303 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
