HCSGD entry for LNX1
1. General information
| Official gene symbol | LNX1 |
|---|---|
| Entrez ID | 84708 |
| Gene full name | ligand of numb-protein X 1, E3 ubiquitin protein ligase |
| Other gene symbols | LNX MPDZ PDZRN2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2221989248 | 0.2937613009 | 0.9034505325 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2672843426 |
| GSE13712_SHEAR | Down | -0.3823288751 |
| GSE13712_STATIC | Up | 0.4238125479 |
| GSE19018 | Down | -0.4751738311 |
| GSE19899_A1 | Up | 0.0363889083 |
| GSE19899_A2 | Down | -0.6322998132 |
| PubMed_21979375_A1 | Down | -0.2660561123 |
| PubMed_21979375_A2 | Down | -0.2843778412 |
| GSE35957 | Up | 0.1459836686 |
| GSE36640 | Up | 0.4972792218 |
| GSE54402 | Down | -0.1898526745 |
| GSE9593 | Up | 0.0538465096 |
| GSE43922 | Up | 0.0254308846 |
| GSE24585 | Up | 0.2444253709 |
| GSE37065 | Down | -0.1251626711 |
| GSE28863_A1 | Up | 0.0602218928 |
| GSE28863_A2 | Up | 0.4550155314 |
| GSE28863_A3 | Up | 0.0779589489 |
| GSE28863_A4 | Up | 0.0067198419 |
| GSE48662 | Down | -0.0527974521 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
