HCSGD entry for GPT2
1. General information
| Official gene symbol | GPT2 |
|---|---|
| Entrez ID | 84706 |
| Gene full name | glutamic pyruvate transaminase (alanine aminotransferase) 2 |
| Other gene symbols | ALT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004021 | L-alanine:2-oxoglutarate aminotransferase activity | EXP IDA | molecular_function |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006103 | 2-oxoglutarate metabolic process | IDA | biological_process |
| GO:0008652 | Cellular amino acid biosynthetic process | TAS | biological_process |
| GO:0009058 | Biosynthetic process | IEA | biological_process |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0042851 | L-alanine metabolic process | IDA | biological_process |
| GO:0042853 | L-alanine catabolic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2382299533 | 0.0959435052 | 0.9240274978 | 0.5904713584 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3617312921 |
| GSE13712_SHEAR | Up | 0.3131096498 |
| GSE13712_STATIC | Up | 0.0145437834 |
| GSE19018 | Up | 0.7729799540 |
| GSE19899_A1 | Up | 0.0766238890 |
| GSE19899_A2 | Down | -0.2148341335 |
| PubMed_21979375_A1 | Up | 0.6738508444 |
| PubMed_21979375_A2 | Down | -0.0442048592 |
| GSE35957 | Down | -0.6674151385 |
| GSE36640 | Down | -0.8390475015 |
| GSE54402 | Up | 0.3126439718 |
| GSE9593 | Down | -0.3020961117 |
| GSE43922 | Up | 0.0495854784 |
| GSE24585 | Down | -0.7175276268 |
| GSE37065 | Down | -0.5181280203 |
| GSE28863_A1 | Down | -0.0644497199 |
| GSE28863_A2 | Down | -0.1015173188 |
| GSE28863_A3 | Up | 0.2500112150 |
| GSE28863_A4 | Down | -0.0315346103 |
| GSE48662 | Up | 0.5619693433 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
| L-Alanine | DB00160 | NUTR00013 |
| Phenelzine | DB00780 | APRD00099 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020600 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028719 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1909-5p | MIMAT0007882 | MIRT035805 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044565 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
