HCSGD entry for SMARCA5

1. General information

Official gene symbolSMARCA5
Entrez ID8467
Gene full nameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Other gene symbolsISWI SNF2H WCRF135 hISWI hSNF2H
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000183Chromatin silencing at rDNAIEAbiological_process
GO:0000793Condensed chromosomeIDAcellular_component
GO:0003677DNA bindingIDAmolecular_function
GO:0004386Helicase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005677Chromatin silencing complexIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006302Double-strand break repairIEAbiological_process
GO:0006334Nucleosome assemblyIDA TASbiological_process
GO:0006338Chromatin remodelingIDAbiological_process
GO:0006352DNA-templated transcription, initiationIDAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0009790Embryo developmentIEAbiological_process
GO:0016584Nucleosome positioningIDAbiological_process
GO:0016589NURF complexIDAcellular_component
GO:0016887ATPase activityIDAmolecular_function
GO:0031213RSF complexIPIcellular_component
GO:0031491Nucleosome bindingIEAmolecular_function
GO:0034080CENP-A containing nucleosome assembly at centromereTASbiological_process
GO:0042393Histone bindingIDAmolecular_function
GO:0043044ATP-dependent chromatin remodelingIMPbiological_process
GO:0043596Nuclear replication forkIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80846388820.09341991950.99999024730.5819895148

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1173852235
GSE13712_SHEARDown-0.0869774901
GSE13712_STATICDown-0.1016892947
GSE19018Down-0.0171750441
GSE19899_A1Down-0.1120240970
GSE19899_A2Down-0.2762537079
PubMed_21979375_A1Down-0.3117856251
PubMed_21979375_A2Down-0.1103206775
GSE35957Down-0.1994631645
GSE36640Down-0.4026039565
GSE54402Up0.0665812196
GSE9593Down-0.6351982702
GSE43922Down-0.0527595956
GSE24585Up0.1284232201
GSE37065Up0.1601278547
GSE28863_A1Up0.8466982100
GSE28863_A2Up0.6192650156
GSE28863_A3Down-0.2330751623
GSE28863_A4Down-0.2154347343
GSE48662Down-0.3163436089

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Beta-D-GlucoseDB02379 EXPT00685 | EXPT00455 | EXPT01603
4-Deoxy-Alpha-D-GlucoseDB02670 EXPT01533

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT036868CLASHFunctional MTI (Weak)23622248
hsa-miR-424-5pMIMAT0001341MIRT042457CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.