HCSGD entry for ACSS1
1. General information
| Official gene symbol | ACSS1 |
|---|---|
| Entrez ID | 84532 |
| Gene full name | acyl-CoA synthetase short-chain family member 1 |
| Other gene symbols | ACAS2L ACECS1 AceCS2L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003987 | Acetate-CoA ligase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | IDA TAS | cellular_component |
| GO:0006069 | Ethanol oxidation | TAS | biological_process |
| GO:0006085 | Acetyl-CoA biosynthetic process | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0016208 | AMP binding | IEA | molecular_function |
| GO:0019413 | Acetate biosynthetic process | IEA | biological_process |
| GO:0019427 | Acetyl-CoA biosynthetic process from acetate | IEA | biological_process |
| GO:0019542 | Propionate biosynthetic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6422748528 | 0.7373693249 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0102999442 |
| GSE13712_SHEAR | Down | -0.1500508320 |
| GSE13712_STATIC | Down | -0.1468791030 |
| GSE19018 | Up | 0.0829105051 |
| GSE19899_A1 | Down | -0.0200589920 |
| GSE19899_A2 | Up | 0.0417286300 |
| PubMed_21979375_A1 | Up | 0.0164283744 |
| PubMed_21979375_A2 | Down | -0.1221196320 |
| GSE35957 | Down | -0.0118085924 |
| GSE36640 | Down | -0.0949547233 |
| GSE54402 | Up | 0.0066357826 |
| GSE9593 | Down | -0.0669360101 |
| GSE43922 | Up | 0.0387935239 |
| GSE24585 | Up | 0.5332780248 |
| GSE37065 | Down | -0.2344863455 |
| GSE28863_A1 | Up | 0.7271286268 |
| GSE28863_A2 | Up | 0.0121408468 |
| GSE28863_A3 | Down | -0.0358811450 |
| GSE28863_A4 | Up | 0.0846526693 |
| GSE48662 | Down | -0.0424169976 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Adenosine triphosphate | DB00171 | NUTR00017 | EXPT00007 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025533 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045786 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046084 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050224 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
