HCSGD entry for CARD11

1. General information

Official gene symbolCARD11
Entrez ID84433
Gene full namecaspase recruitment domain family, member 11
Other gene symbolsBENTA BIMP3 CARMA1 PPBL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001819Positive regulation of cytokine productionIMPbiological_process
GO:0004385Guanylate kinase activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIDA IEA TAScellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0008152Metabolic processNASbiological_process
GO:0016310PhosphorylationNASbiological_process
GO:0030890Positive regulation of B cell proliferationIEAbiological_process
GO:0031295T cell costimulationIDAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042101T cell receptor complexIDAcellular_component
GO:0042102Positive regulation of T cell proliferationIEAbiological_process
GO:0042981Regulation of apoptotic processIEAbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIEAbiological_process
GO:0045061Thymic T cell selectionIEAbiological_process
GO:0045086Positive regulation of interleukin-2 biosynthetic processIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045121Membrane raftIDAcellular_component
GO:0045577Regulation of B cell differentiationIEAbiological_process
GO:0045580Regulation of T cell differentiationIEAbiological_process
GO:0046939Nucleotide phosphorylationNASbiological_process
GO:0050700CARD domain bindingIPImolecular_function
GO:0050776Regulation of immune responseIEAbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80334935600.79662597550.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1317222016
GSE13712_SHEARUp0.2055979709
GSE13712_STATICUp0.2479774496
GSE19018Up0.0922260852
GSE19899_A1Up0.0325768919
GSE19899_A2Down-0.0299542752
PubMed_21979375_A1Down-0.0307667324
PubMed_21979375_A2Down-0.0526910481
GSE35957Up0.1700724620
GSE36640Down-0.0404035297
GSE54402Down-0.0135142704
GSE9593Down-0.0435591745
GSE43922Up0.0212561550
GSE24585Up0.1007807559
GSE37065Down-0.0885039161
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0210527467

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020564Reporter assay;OtherFunctional MTI20584899
hsa-miR-330-5pMIMAT0004693MIRT038232CLASHFunctional MTI (Weak)23622248
hsa-miR-146b-5pMIMAT0002809MIRT041621CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.