HCSGD entry for HOOK3
1. General information
| Official gene symbol | HOOK3 |
|---|---|
| Entrez ID | 84376 |
| Gene full name | hook homolog 3 (Drosophila) |
| Other gene symbols | HK3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000242 | Pericentriolar material | ISS | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005801 | Cis-Golgi network | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA ISS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007032 | Endosome organization | IMP | biological_process |
| GO:0007040 | Lysosome organization | IMP | biological_process |
| GO:0008017 | Microtubule binding | IDA | molecular_function |
| GO:0008333 | Endosome to lysosome transport | IMP | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0022027 | Interkinetic nuclear migration | ISS | biological_process |
| GO:0030897 | HOPS complex | IDA | cellular_component |
| GO:0031122 | Cytoplasmic microtubule organization | IMP | biological_process |
| GO:0034451 | Centriolar satellite | IEA | cellular_component |
| GO:0034454 | Microtubule anchoring at centrosome | ISS | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0045022 | Early endosome to late endosome transport | IMP | biological_process |
| GO:0050768 | Negative regulation of neurogenesis | ISS | biological_process |
| GO:0051645 | Golgi localization | IMP | biological_process |
| GO:0070695 | FHF complex | IDA | cellular_component |
| GO:0071539 | Protein localization to centrosome | ISS | biological_process |
| GO:0097150 | Neuronal stem cell maintenance | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4248091334 | 0.1957814027 | 0.9999902473 | 0.8573830534 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3755813843 |
| GSE13712_SHEAR | Up | 0.1919645559 |
| GSE13712_STATIC | Up | 0.0885615542 |
| GSE19018 | Up | 0.0327807405 |
| GSE19899_A1 | Down | -0.3259460064 |
| GSE19899_A2 | Down | -0.1191579427 |
| PubMed_21979375_A1 | Down | -0.2676910342 |
| PubMed_21979375_A2 | Down | -0.2920716994 |
| GSE35957 | Up | 0.2287719231 |
| GSE36640 | Up | 0.0635835240 |
| GSE54402 | Down | -0.1340865515 |
| GSE9593 | Down | -0.1061733663 |
| GSE43922 | Down | -0.2442748843 |
| GSE24585 | Down | -0.0760858468 |
| GSE37065 | Up | 0.1295290722 |
| GSE28863_A1 | Up | 0.4953918381 |
| GSE28863_A2 | Up | 0.7788972240 |
| GSE28863_A3 | Down | -0.0507775455 |
| GSE28863_A4 | Down | -0.3535937372 |
| GSE48662 | Up | 0.5527416020 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026745 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039786 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181a-3p | MIMAT0000270 | MIRT046999 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT047303 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
