HCSGD entry for SOAT2

1. General information

Official gene symbolSOAT2
Entrez ID8435
Gene full namesterol O-acyltransferase 2
Other gene symbolsACACT2 ACAT2 ARGP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000062Fatty-acyl-CoA bindingIDAmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0005903Brush borderIDAcellular_component
GO:0008203Cholesterol metabolic processIDAbiological_process
GO:0008374O-acyltransferase activityIEAmolecular_function
GO:0010742Macrophage derived foam cell differentiationTASbiological_process
GO:0015485Cholesterol bindingIDAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016746Transferase activity, transferring acyl groupsTASmolecular_function
GO:0030299Intestinal cholesterol absorptionICbiological_process
GO:0033344Cholesterol effluxIMPbiological_process
GO:0034379Very-low-density lipoprotein particle assemblyIMPbiological_process
GO:0034435Cholesterol esterificationIDAbiological_process
GO:0034736Cholesterol O-acyltransferase activityIDAmolecular_function
GO:0042632Cholesterol homeostasisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39898549450.90869109840.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0272981420
GSE13712_SHEARUp0.1078072969
GSE13712_STATICDown-0.0794678524
GSE19018Down-0.0689169373
GSE19899_A1Up0.0528293621
GSE19899_A2Up0.1397314219
PubMed_21979375_A1Up0.3242841539
PubMed_21979375_A2Down-0.0060530801
GSE35957Up0.2022361419
GSE36640Down-0.0428560624
GSE54402Up0.2087526915
GSE9593Down-0.0245528705
GSE43922Up0.0264328522
GSE24585Up0.0449078959
GSE37065Down-0.0458075789
GSE28863_A1Up0.1050158173
GSE28863_A2Up0.0368691619
GSE28863_A3Up0.2360846504
GSE28863_A4Up0.1748704594
GSE48662Down-0.0171442851

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

HesperetinDB01094 APRD00117

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018756MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.