HCSGD entry for GFM2
1. General information
| Official gene symbol | GFM2 |
|---|---|
| Entrez ID | 84340 |
| Gene full name | G elongation factor, mitochondrial 2 |
| Other gene symbols | EF-G2mt EFG2 MRRF2 MST027 RRF2 RRF2mt hEFG2 mEF-G 2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003746 | Translation elongation factor activity | IDA | molecular_function |
| GO:0003924 | GTPase activity | IDA IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | IDA | biological_process |
| GO:0032543 | Mitochondrial translation | IDA | biological_process |
| GO:0032790 | Ribosome disassembly | IDA | biological_process |
| GO:0070125 | Mitochondrial translational elongation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1591244140 | 0.4007638730 | 0.7908735838 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4973409182 |
| GSE13712_SHEAR | Down | -0.2347516710 |
| GSE13712_STATIC | Up | 0.0274888305 |
| GSE19018 | Up | 0.2398687533 |
| GSE19899_A1 | Up | 0.1987550359 |
| GSE19899_A2 | Up | 0.3518464399 |
| PubMed_21979375_A1 | Up | 0.2998591777 |
| PubMed_21979375_A2 | Down | -0.1885153825 |
| GSE35957 | Up | 0.0700457465 |
| GSE36640 | Up | 0.4734043031 |
| GSE54402 | Up | 0.0662731960 |
| GSE9593 | Up | 0.0757771884 |
| GSE43922 | Up | 0.1012443937 |
| GSE24585 | Up | 0.3468644418 |
| GSE37065 | Up | 0.0984898475 |
| GSE28863_A1 | Down | -0.2991961654 |
| GSE28863_A2 | Up | 0.1553724750 |
| GSE28863_A3 | Down | -0.8789692179 |
| GSE28863_A4 | Down | -0.2456319962 |
| GSE48662 | Down | -0.3647616947 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019732 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032195 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
