HCSGD entry for APOPT1


1. General information

Official gene symbolAPOPT1
Entrez ID84334
Gene full nameapoptogenic 1, mitochondrial
Other gene symbolsAPOP1 C14orf153
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005739MitochondrionIEAcellular_component
GO:0034393Positive regulation of smooth muscle cell apoptotic processIEAbiological_process
GO:0043280Positive regulation of cysteine-type endopeptidase activity involved in apoptotic processIEAbiological_process
GO:0090200Positive regulation of release of cytochrome c from mitochondriaIEAbiological_process
GO:0097193Intrinsic apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89750780750.30263373350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0389314506
GSE13712_SHEARUp0.1445594413
GSE13712_STATICUp0.1236448707
GSE19018Down-0.0392083465
GSE19899_A1Down-0.1061668306
GSE19899_A2Up0.0094872585
PubMed_21979375_A1Up0.1063616608
PubMed_21979375_A2Down-0.3291442610
GSE35957Down-0.1087760333
GSE36640Up0.0505944379
GSE54402Up0.0566158768
GSE9593Down-0.2148950978
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.2470137021
GSE28863_A2Down-0.2022013265
GSE28863_A3Down-0.5312398906
GSE28863_A4Up0.2122019588
GSE48662Up0.1055795597

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT039923CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043520CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.