HCSGD entry for CASP10
1. General information
| Official gene symbol | CASP10 |
|---|---|
| Entrez ID | 843 |
| Gene full name | caspase 10, apoptosis-related cysteine peptidase |
| Other gene symbols | ALPS2 FLICE2 MCH4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004197 | Cysteine-type endopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0042981 | Regulation of apoptotic process | IEA | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP RCA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0097190 | Apoptotic signaling pathway | TAS | biological_process |
| GO:0097342 | Ripoptosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3211580031 | 0.9494825159 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0199345939 |
| GSE13712_SHEAR | Up | 0.0827925257 |
| GSE13712_STATIC | Down | -0.0278590513 |
| GSE19018 | Up | 0.0972306718 |
| GSE19899_A1 | Up | 0.0785633394 |
| GSE19899_A2 | Up | 0.1221049671 |
| PubMed_21979375_A1 | Up | 0.1747281244 |
| PubMed_21979375_A2 | Down | -0.0419064540 |
| GSE35957 | Up | 0.0263258610 |
| GSE36640 | Up | 0.0435776266 |
| GSE54402 | Up | 0.0536452828 |
| GSE9593 | Up | 0.0707640691 |
| GSE43922 | Up | 0.0020598840 |
| GSE24585 | Up | 0.4700097297 |
| GSE37065 | Up | 0.2296815988 |
| GSE28863_A1 | Up | 0.2495392232 |
| GSE28863_A2 | Up | 0.1671787059 |
| GSE28863_A3 | Down | -0.0921739817 |
| GSE28863_A4 | Up | 0.0229180311 |
| GSE48662 | Up | 0.2121690572 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22829758 | These include COL4A3, CFLAR, GULP1, PDCD1, CASP10, PAX3, BOK, HSPD1, PITX2, and PML |
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