HCSGD entry for MEX3B
1. General information
| Official gene symbol | MEX3B |
|---|---|
| Entrez ID | 84206 |
| Gene full name | mex-3 homolog B (C. elegans) |
| Other gene symbols | MEX-3B RKHD3 RNF195 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000932 | Cytoplasmic mRNA processing body | IEA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | ISS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | ISS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0046777 | Protein autophosphorylation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9943555792 | 0.0013871851 | 0.9999902473 | 0.0718742126 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4215548699 |
| GSE13712_SHEAR | Down | -0.2246897652 |
| GSE13712_STATIC | Down | -1.1448766822 |
| GSE19018 | Up | 0.0887318204 |
| GSE19899_A1 | Down | -0.3288459618 |
| GSE19899_A2 | Down | -2.4467858620 |
| PubMed_21979375_A1 | Down | -0.8878899706 |
| PubMed_21979375_A2 | Down | -1.1360008352 |
| GSE35957 | Down | -0.8836647701 |
| GSE36640 | Down | -2.1453254059 |
| GSE54402 | Down | -1.1682825938 |
| GSE9593 | Down | -0.5090693030 |
| GSE43922 | Up | 0.0295118918 |
| GSE24585 | Down | -0.0450000380 |
| GSE37065 | Down | -0.2012579201 |
| GSE28863_A1 | Down | -0.2581975757 |
| GSE28863_A2 | Down | -0.2021401470 |
| GSE28863_A3 | Down | -0.0101092603 |
| GSE28863_A4 | Up | 0.1533029205 |
| GSE48662 | Down | -0.6367008545 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024256 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026856 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040581 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24326307 | HOTAIR associates with E3 ubiquitin ligases bearing RNA-binding domains, Dzip3 and Mex3b, as well as with their respective ubiquitination substrates, Ataxin-1 and Snurportin-1 |
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