HCSGD entry for SETD3
1. General information
| Official gene symbol | SETD3 |
|---|---|
| Entrez ID | 84193 |
| Gene full name | SET domain containing 3 |
| Other gene symbols | C14orf154 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000790 | Nuclear chromatin | IEA | cellular_component |
| GO:0001102 | RNA polymerase II activating transcription factor binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IEA ISS | molecular_function |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0010452 | Histone H3-K36 methylation | ISS | biological_process |
| GO:0018023 | Peptidyl-lysine trimethylation | ISS | biological_process |
| GO:0018026 | Peptidyl-lysine monomethylation | ISS | biological_process |
| GO:0018027 | Peptidyl-lysine dimethylation | ISS | biological_process |
| GO:0042800 | Histone methyltransferase activity (H3-K4 specific) | IEA | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | ISS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046975 | Histone methyltransferase activity (H3-K36 specific) | IEA ISS | molecular_function |
| GO:0051149 | Positive regulation of muscle cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1992765776 | 0.9195836366 | 0.8618698374 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0610356730 |
| GSE13712_SHEAR | Down | -0.2555575272 |
| GSE13712_STATIC | Up | 0.1669103931 |
| GSE19018 | Up | 0.0416081786 |
| GSE19899_A1 | Up | 0.1461860568 |
| GSE19899_A2 | Up | 0.6064379134 |
| PubMed_21979375_A1 | Up | 0.7046747860 |
| PubMed_21979375_A2 | Up | 0.2445945491 |
| GSE35957 | Down | -0.0001996718 |
| GSE36640 | Up | 0.2589146505 |
| GSE54402 | Up | 0.2294308005 |
| GSE9593 | Down | -0.1921164456 |
| GSE43922 | Up | 0.0304865276 |
| GSE24585 | Up | 0.0387445231 |
| GSE37065 | Down | -0.0834478337 |
| GSE28863_A1 | Up | 0.0420480954 |
| GSE28863_A2 | Up | 0.2131820215 |
| GSE28863_A3 | Down | -0.5186536996 |
| GSE28863_A4 | Up | 0.2391936382 |
| GSE48662 | Down | -0.0436413011 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025247 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-320a | MIMAT0000510 | MIRT044857 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
