HCSGD entry for LOXL4
1. General information
| Official gene symbol | LOXL4 |
|---|---|
| Entrez ID | 84171 |
| Gene full name | lysyl oxidase-like 4 |
| Other gene symbols | LOXC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004720 | Protein-lysine 6-oxidase activity | IEA | molecular_function |
| GO:0005044 | Scavenger receptor activity | IEA | molecular_function |
| GO:0005507 | Copper ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0043235 | Receptor complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1034098742 | 0.1479652787 | 0.6689238879 | 0.7437482054 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1290292491 |
| GSE13712_SHEAR | Down | -0.0288326858 |
| GSE13712_STATIC | Up | 0.2493281251 |
| GSE19018 | Up | 0.5816839825 |
| GSE19899_A1 | Up | 0.0250379812 |
| GSE19899_A2 | Up | 0.3188204247 |
| PubMed_21979375_A1 | Down | -1.2572604198 |
| PubMed_21979375_A2 | Down | -0.2432545811 |
| GSE35957 | Up | 1.1244558251 |
| GSE36640 | Up | 0.0065208463 |
| GSE54402 | Down | -0.9379544552 |
| GSE9593 | Down | -0.0795918266 |
| GSE43922 | Down | -0.0027982903 |
| GSE24585 | Up | 0.2750501655 |
| GSE37065 | Down | -0.8241937644 |
| GSE28863_A1 | Up | 0.0816763376 |
| GSE28863_A2 | Up | 1.0382747065 |
| GSE28863_A3 | Down | -0.5365114835 |
| GSE28863_A4 | Up | 0.1319231812 |
| GSE48662 | Up | 0.6253784600 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017606 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022543 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
