HCSGD entry for NLRC5

1. General information

Official gene symbolNLRC5
Entrez ID84166
Gene full nameNLR family, CARD domain containing 5
Other gene symbolsCLR16.1 NOD27 NOD4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIDA IEA TAScellular_component
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDA IEAbiological_process
GO:0032480Negative regulation of type I interferon productionTASbiological_process
GO:0043549Regulation of kinase activityIDAbiological_process
GO:0045087Innate immune responseIEA IMP TASbiological_process
GO:0045345Positive regulation of MHC class I biosynthetic processIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0051607Defense response to virusIEPbiological_process
GO:0060335Positive regulation of interferon-gamma-mediated signaling pathwayIDA IMPbiological_process
GO:0060339Negative regulation of type I interferon-mediated signaling pathwayIDA IEAbiological_process
GO:0060340Positive regulation of type I interferon-mediated signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09628278180.15768925570.64910222220.7670609314

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2682926247
GSE13712_SHEARUp1.7952809816
GSE13712_STATICUp1.5301181603
GSE19018Down-0.2839720643
GSE19899_A1Down-0.3021029212
GSE19899_A2Down-0.2894690094
PubMed_21979375_A1Down-1.4781706196
PubMed_21979375_A2Up0.4314050347
GSE35957Down-0.2424225844
GSE36640Up0.5782794254
GSE54402Up0.2896808818
GSE9593Down-0.4932602007
GSE43922Down-0.0121617680
GSE24585Down-0.0626924231
GSE37065Up0.4905128123
GSE28863_A1Up0.2043274354
GSE28863_A2Up0.4517712035
GSE28863_A3Down-0.1289367202
GSE28863_A4Up0.0186066654
GSE48662Down-0.1243943564

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.