HCSGD entry for BCAR3
1. General information
| Official gene symbol | BCAR3 |
|---|---|
| Entrez ID | 8412 |
| Gene full name | breast cancer anti-estrogen resistance 3 |
| Other gene symbols | NSP2 SH2D3B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0042493 | Response to drug | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2589072908 | 0.1397264276 | 0.9523144174 | 0.7192061400 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9165672660 |
| GSE13712_SHEAR | Down | -0.0381468591 |
| GSE13712_STATIC | Up | 0.2740910417 |
| GSE19018 | Down | -0.1356544702 |
| GSE19899_A1 | Up | 0.9511192504 |
| GSE19899_A2 | Up | 0.3828964316 |
| PubMed_21979375_A1 | Up | 0.0629373265 |
| PubMed_21979375_A2 | Up | 0.5759293201 |
| GSE35957 | Up | 0.1368114818 |
| GSE36640 | Up | 0.0475760085 |
| GSE54402 | Down | -0.0774045322 |
| GSE9593 | Up | 0.0980418873 |
| GSE43922 | Up | 0.1227898689 |
| GSE24585 | Up | 0.0010400296 |
| GSE37065 | Down | -0.1088767837 |
| GSE28863_A1 | Down | -0.2534392409 |
| GSE28863_A2 | Up | 0.2778396228 |
| GSE28863_A3 | Down | -0.0789435975 |
| GSE28863_A4 | Down | -0.3094149797 |
| GSE48662 | Down | -1.0438346663 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042690 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
