HCSGD entry for ANKRD27
1. General information
| Official gene symbol | ANKRD27 |
|---|---|
| Entrez ID | 84079 |
| Gene full name | ankyrin repeat domain 27 (VPS9 domain) |
| Other gene symbols | VARP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005769 | Early endosome | IDA | cellular_component |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0045022 | Early endosome to late endosome transport | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4400064967 | 0.4309765358 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3748500888 |
| GSE13712_SHEAR | Up | 0.2785851024 |
| GSE13712_STATIC | Down | -0.0348306919 |
| GSE19018 | Down | -0.0872151503 |
| GSE19899_A1 | Up | 0.1587244543 |
| GSE19899_A2 | Up | 0.2282457374 |
| PubMed_21979375_A1 | Up | 0.5432190323 |
| PubMed_21979375_A2 | Up | 0.1164533688 |
| GSE35957 | Up | 0.3873435437 |
| GSE36640 | Down | -0.2463399517 |
| GSE54402 | Up | 0.2905759582 |
| GSE9593 | Up | 0.1767907131 |
| GSE43922 | Up | 0.0274260461 |
| GSE24585 | Down | -0.1389435760 |
| GSE37065 | Down | -0.2212181501 |
| GSE28863_A1 | Down | -0.0835202977 |
| GSE28863_A2 | Up | 0.2196571139 |
| GSE28863_A3 | Down | -0.6204318473 |
| GSE28863_A4 | Down | -0.0435246724 |
| GSE48662 | Up | 0.0822370593 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002637 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002637 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038857 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-500a-3p | MIMAT0002871 | MIRT041158 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042819 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050984 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
