HCSGD entry for OBSCN
1. General information
Official gene symbol | OBSCN |
---|---|
Entrez ID | 84033 |
Gene full name | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
Other gene symbols | ARHGEF30 UNC89 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005516 | Calmodulin binding | IEA | molecular_function |
GO:0005524 | ATP binding | IEA | molecular_function |
GO:0005829 | Cytosol | TAS | cellular_component |
GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
GO:0007275 | Multicellular organismal development | IEA | biological_process |
GO:0008307 | Structural constituent of muscle | NAS | molecular_function |
GO:0030016 | Myofibril | NAS | cellular_component |
GO:0030018 | Z disc | ISS | cellular_component |
GO:0030506 | Ankyrin binding | IPI | molecular_function |
GO:0031430 | M band | ISS | cellular_component |
GO:0031432 | Titin binding | IPI | molecular_function |
GO:0036309 | Protein localization to M-band | ISS | biological_process |
GO:0043065 | Positive regulation of apoptotic process | TAS | biological_process |
GO:0045214 | Sarcomere organization | TAS | biological_process |
GO:0046872 | Metal ion binding | IEA | molecular_function |
GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
GO:0097190 | Apoptotic signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.4453667186 | 0.9538686752 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.0049239690 |
GSE13712_SHEAR | Up | 0.1834967967 |
GSE13712_STATIC | Up | 0.0346612762 |
GSE19018 | Up | 0.0493945553 |
GSE19899_A1 | Up | 0.0252975213 |
GSE19899_A2 | Up | 0.1010611022 |
PubMed_21979375_A1 | Down | -0.0063432805 |
PubMed_21979375_A2 | Up | 0.0836376159 |
GSE35957 | Up | 0.1462381902 |
GSE36640 | Up | 0.1597797413 |
GSE54402 | Up | 0.0140527074 |
GSE9593 | Down | -0.0200105580 |
GSE43922 | Up | 0.0274089756 |
GSE24585 | Up | 0.2457707158 |
GSE37065 | Down | -0.0188514990 |
GSE28863_A1 | Down | -0.0859127495 |
GSE28863_A2 | Up | 0.0608077523 |
GSE28863_A3 | Up | 0.2779980500 |
GSE28863_A4 | Up | 0.0693051987 |
GSE48662 | Up | 0.0917987481 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-155-5p | MIMAT0000646 | MIRT020811 | Proteomics | Functional MTI (Weak) | 18668040 |
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