HCSGD entry for PLA2G10

1. General information

Official gene symbolPLA2G10
Entrez ID8399
Gene full namephospholipase A2, group X
Other gene symbolsGXPLA2 GXSPLA2 SPLA2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004620Phospholipase activityISSmolecular_function
GO:0004623Phospholipase A2 activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0006644Phospholipid metabolic processIEA TASbiological_process
GO:0006654Phosphatidic acid biosynthetic processTASbiological_process
GO:0007411Axon guidanceIDAbiological_process
GO:0010744Positive regulation of macrophage derived foam cell differentiationICbiological_process
GO:0010884Positive regulation of lipid storageIMPbiological_process
GO:0016042Lipid catabolic processIEAbiological_process
GO:0019369Arachidonic acid metabolic processNASbiological_process
GO:0032270Positive regulation of cellular protein metabolic processIMPbiological_process
GO:0032308Positive regulation of prostaglandin secretionIMPbiological_process
GO:0036148Phosphatidylglycerol acyl-chain remodelingTASbiological_process
GO:0036149Phosphatidylinositol acyl-chain remodelingTASbiological_process
GO:0036150Phosphatidylserine acyl-chain remodelingTASbiological_process
GO:0036151Phosphatidylcholine acyl-chain remodelingTASbiological_process
GO:0036152Phosphatidylethanolamine acyl-chain remodelingTASbiological_process
GO:0042632Cholesterol homeostasisISSbiological_process
GO:0043030Regulation of macrophage activationIMPbiological_process
GO:0043433Negative regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
GO:0051977Lysophospholipid transportIDAbiological_process
GO:0090238Positive regulation of arachidonic acid secretionISSbiological_process
GO:0090370Negative regulation of cholesterol effluxISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99611562630.01518899740.99999024730.2421499697

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1896496882
GSE28863_A2Down-0.9828185599
GSE28863_A3Down-0.8058907413
GSE28863_A4Down-0.2891272605
GSE48662Down-0.1365498264

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018251MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.