HCSGD entry for STK40


1. General information

Official gene symbolSTK40
Entrez ID83931
Gene full nameserine/threonine kinase 40
Other gene symbolsRP11-268J15.4 SHIK SgK495
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23392862730.81310844190.91763380371.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0039863898
GSE13712_SHEARUp0.0394176808
GSE13712_STATICDown-0.2779303970
GSE19018Down-0.0686432149
GSE19899_A1Down-0.0511137257
GSE19899_A2Up0.6289299373
PubMed_21979375_A1Up0.6656872250
PubMed_21979375_A2Up0.7426796071
GSE35957Down-0.0482215911
GSE36640Up0.3540023885
GSE54402Down-0.0095925736
GSE9593Up0.2037530714
GSE43922Up0.1101004516
GSE24585Down-0.1412569646
GSE37065Down-0.0290575548
GSE28863_A1Up0.0022257202
GSE28863_A2Up0.1436920374
GSE28863_A3Down-0.3016835552
GSE28863_A4Down-0.0799056790
GSE48662Up0.1478354735

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-31-5pMIMAT0000089MIRT007319Luciferase reporter assayFunctional MTI23233723
hsa-miR-31-5pMIMAT0000089MIRT007319CLASHFunctional MTI (Weak)23622248
hsa-miR-7-5pMIMAT0000252MIRT025713SequencingFunctional MTI (Weak)20371350
hsa-miR-196a-5pMIMAT0000226MIRT026054SequencingFunctional MTI (Weak)20371350
hsa-miR-103a-3pMIMAT0000101MIRT027005SequencingFunctional MTI (Weak)20371350
hsa-let-7d-5pMIMAT0000065MIRT032155SequencingFunctional MTI (Weak)20371350
hsa-miR-940MIMAT0004983MIRT036586CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039827CLASHFunctional MTI (Weak)23622248
hsa-miR-106b-5pMIMAT0000680MIRT044350CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047110CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.