HCSGD entry for BCO2

1. General information

Official gene symbolBCO2
Entrez ID83875
Gene full namebeta-carotene oxygenase 2
Other gene symbolsB-DIOX-II BCDO2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005622IntracellularICcellular_component
GO:0005739MitochondrionISS TAScellular_component
GO:0016116Carotenoid metabolic processISSbiological_process
GO:0016119Carotene metabolic processIDAbiological_process
GO:0016121Carotene catabolic processIDAbiological_process
GO:0016702Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenIDAmolecular_function
GO:0042573Retinoic acid metabolic processNASbiological_process
GO:0042574Retinal metabolic processNASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051881Regulation of mitochondrial membrane potentialISSbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
GO:2000377Regulation of reactive oxygen species metabolic processISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.42515710270.82508482580.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0450283530
GSE13712_SHEARUp0.2300728015
GSE13712_STATICUp0.2037295500
GSE19018Up0.3176921366
GSE19899_A1Up0.0415144241
GSE19899_A2Down-0.0642500773
PubMed_21979375_A1Down-0.3831187618
PubMed_21979375_A2Down-0.0032588609
GSE35957Down-0.0811763396
GSE36640Up0.6792924202
GSE54402Down-0.0975334654
GSE9593Down-0.0094642588
GSE43922Up0.0156482577
GSE24585Down-0.0203687244
GSE37065Up0.1183602305
GSE28863_A1Down-0.0307041914
GSE28863_A2Up0.0231555238
GSE28863_A3Down-0.1184873497
GSE28863_A4Up0.0215167107
GSE48662Up0.1509720558

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.