HCSGD entry for JAM3

1. General information

Official gene symbolJAM3
Entrez ID83700
Gene full namejunctional adhesion molecule 3
Other gene symbolsJAM-2 JAM-3 JAM-C JAMC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIDAbiological_process
GO:0001780Neutrophil homeostasisIEAbiological_process
GO:0002250Adaptive immune responseIEAbiological_process
GO:0002318Myeloid progenitor cell differentiationIEAbiological_process
GO:0002523Leukocyte migration involved in inflammatory responseIEAbiological_process
GO:0005178Integrin bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005923Tight junctionIEAcellular_component
GO:0007160Cell-matrix adhesionIEAbiological_process
GO:0007286Spermatid developmentIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019226Transmission of nerve impulseIEAbiological_process
GO:0030010Establishment of cell polarityIEAbiological_process
GO:0030057DesmosomeIDAcellular_component
GO:0033010Paranodal junctionIEAcellular_component
GO:0042552MyelinationIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0043220Schmidt-Lanterman incisureIEAcellular_component
GO:0044291Cell-cell contact zoneIDAcellular_component
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0050900Leukocyte migrationTASbiological_process
GO:0090022Regulation of neutrophil chemotaxisIDAbiological_process
GO:0090138Regulation of actin cytoskeleton organization by cell-cell adhesionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12359343110.51992864630.71844140901.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0373875625
GSE13712_SHEARDown-0.2055000164
GSE13712_STATICDown-0.8363694635
GSE19018Down-0.0758058668
GSE19899_A1Down-0.1783052906
GSE19899_A2Up0.0073791156
PubMed_21979375_A1Up0.3339165307
PubMed_21979375_A2Down-1.3516836094
GSE35957Up0.2239193740
GSE36640Up0.1970162663
GSE54402Down-0.0661184125
GSE9593Up0.6304362519
GSE43922Up0.0156934478
GSE24585Up0.3156058623
GSE37065Up0.0829151692
GSE28863_A1Up0.7127939239
GSE28863_A2Up0.3865617627
GSE28863_A3Up0.2291485214
GSE28863_A4Up0.0530301086
GSE48662Up0.5077737065

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.