HCSGD entry for SESN2
1. General information
| Official gene symbol | SESN2 |
|---|---|
| Entrez ID | 83667 |
| Gene full name | sestrin 2 |
| Other gene symbols | HI95 SES2 SEST2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007050 | Cell cycle arrest | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0073734547 | 0.8027185023 | 0.2247319444 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5118734096 |
| GSE13712_SHEAR | Up | 0.1777731210 |
| GSE13712_STATIC | Up | 0.4868043787 |
| GSE19018 | Up | 0.2160464405 |
| GSE19899_A1 | Up | 0.1936591514 |
| GSE19899_A2 | Up | 0.6198774632 |
| PubMed_21979375_A1 | Up | 1.1525048288 |
| PubMed_21979375_A2 | Up | 1.0443346743 |
| GSE35957 | Down | -0.1931699147 |
| GSE36640 | Up | 0.8886105697 |
| GSE54402 | Down | -0.1766284529 |
| GSE9593 | Up | 0.8261764003 |
| GSE43922 | Up | 0.3549710473 |
| GSE24585 | Up | 0.6769218363 |
| GSE37065 | Down | -0.3551266125 |
| GSE28863_A1 | Up | 0.1059205375 |
| GSE28863_A2 | Down | -0.1585096466 |
| GSE28863_A3 | Up | 0.0598130304 |
| GSE28863_A4 | Down | -0.5196259007 |
| GSE48662 | Up | 0.2721899760 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016428 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017581 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-484 | MIMAT0002174 | MIRT041989 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052416 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
