HCSGD entry for CCM2

1. General information

Official gene symbolCCM2
Entrez ID83605
Gene full namecerebral cavernous malformation 2
Other gene symbolsC7orf22 OSM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001570VasculogenesisIMPbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001885Endothelial cell developmentIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0007229Integrin-mediated signaling pathwayTASbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0045216Cell-cell junction organizationIEAbiological_process
GO:0048839Inner ear developmentIEAbiological_process
GO:0048845Venous blood vessel morphogenesisIEAbiological_process
GO:0051403Stress-activated MAPK cascadeTASbiological_process
GO:0060039Pericardium developmentIEAbiological_process
GO:0060837Blood vessel endothelial cell differentiationIEAbiological_process
GO:0061154Endothelial tube morphogenesisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29244809090.64582722540.99258880721.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2479530416
GSE13712_SHEARUp0.1074013791
GSE13712_STATICUp0.1568669020
GSE19018Up0.0818860805
GSE19899_A1Up0.1393655745
GSE19899_A2Up0.3968219342
PubMed_21979375_A1Down-0.1660266604
PubMed_21979375_A2Up0.3412891836
GSE35957Down-0.4012648427
GSE36640Down-0.0846866178
GSE54402Up0.2566950710
GSE9593Down-0.0450598691
GSE43922Up0.2536506597
GSE24585Down-0.1872507097
GSE37065Down-0.1933589063
GSE28863_A1Down-0.1828429114
GSE28863_A2Up0.1415045240
GSE28863_A3Down-0.3027026346
GSE28863_A4Down-0.0550205587
GSE48662Up0.0332820981

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.