HCSGD entry for UCK1
1. General information
| Official gene symbol | UCK1 |
|---|---|
| Entrez ID | 83549 |
| Gene full name | uridine-cytidine kinase 1 |
| Other gene symbols | URK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004849 | Uridine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006206 | Pyrimidine nucleobase metabolic process | TAS | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0016773 | Phosphotransferase activity, alcohol group as acceptor | IEA | molecular_function |
| GO:0019206 | Nucleoside kinase activity | EXP | molecular_function |
| GO:0043097 | Pyrimidine nucleoside salvage | TAS | biological_process |
| GO:0044206 | UMP salvage | IEA | biological_process |
| GO:0044211 | CTP salvage | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8859158087 | 0.3335467687 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0865211584 |
| GSE13712_SHEAR | Down | -0.0356917547 |
| GSE13712_STATIC | Down | -0.2572742595 |
| GSE19018 | Down | -0.1024437478 |
| GSE19899_A1 | Down | -0.1388936041 |
| GSE19899_A2 | Down | -0.3136964442 |
| PubMed_21979375_A1 | Up | 0.4772691489 |
| PubMed_21979375_A2 | Down | -0.3212153142 |
| GSE35957 | Down | -0.2683762099 |
| GSE36640 | Down | -0.0595943636 |
| GSE54402 | Up | 0.0794651620 |
| GSE9593 | Up | 0.3080612148 |
| GSE43922 | Down | -0.0574673625 |
| GSE24585 | Down | -0.0655459036 |
| GSE37065 | Down | -0.0562692629 |
| GSE28863_A1 | Down | -0.1108606497 |
| GSE28863_A2 | Down | -0.0828880473 |
| GSE28863_A3 | Up | 0.1419270130 |
| GSE28863_A4 | Up | 0.0610523663 |
| GSE48662 | Up | 0.0326088877 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024597 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026790 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-326 | MIMAT0000756 | MIRT043656 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052275 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
