HCSGD entry for HIST1H3A
1. General information
| Official gene symbol | HIST1H3A |
|---|---|
| Entrez ID | 8350 |
| Gene full name | histone cluster 1, H3a |
| Other gene symbols | H3/A H3FA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000786 | Nucleosome | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006334 | Nucleosome assembly | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
| GO:0060968 | Regulation of gene silencing | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7598152692 | 0.0718962767 | 0.9999902473 | 0.5049092800 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0884796843 |
| GSE13712_SHEAR | Up | 0.4298441729 |
| GSE13712_STATIC | Down | -0.1252122437 |
| GSE19018 | Down | -0.0783851758 |
| GSE19899_A1 | Down | -0.1013678004 |
| GSE19899_A2 | Down | -0.1247614480 |
| PubMed_21979375_A1 | Down | -0.4738664463 |
| PubMed_21979375_A2 | Down | -0.0476692400 |
| GSE35957 | Up | 0.0521433390 |
| GSE36640 | Down | -1.1725203292 |
| GSE54402 | Down | -0.1728603115 |
| GSE9593 | Up | 0.1922054011 |
| GSE43922 | Down | -1.1562574417 |
| GSE24585 | Up | 0.9512825365 |
| GSE37065 | Down | -0.6045297579 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1992053431 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025485 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036260 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3909 | MIMAT0018183 | MIRT052885 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
