HCSGD entry for CAPZB


1. General information

Official gene symbolCAPZB
Entrez ID832
Gene full namecapping protein (actin filament) muscle Z-line, beta
Other gene symbolsCAPB CAPPB CAPZ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001669Acrosomal vesicleIEAcellular_component
GO:0003779Actin bindingIEA TASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonTAScellular_component
GO:0006928Cellular component movementTASbiological_process
GO:0007010Cytoskeleton organizationIMPbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008290F-actin capping protein complexIEAcellular_component
GO:0014704Intercalated discIEAcellular_component
GO:0015629Actin cytoskeletonTAScellular_component
GO:0016020MembraneIEAcellular_component
GO:0022604Regulation of cell morphogenesisIMPbiological_process
GO:0030018Z discIEAcellular_component
GO:0030027LamellipodiumIEAcellular_component
GO:0030032Lamellipodium assemblyIEAbiological_process
GO:0030036Actin cytoskeleton organizationIEAbiological_process
GO:0030863Cortical cytoskeletonIEAcellular_component
GO:0031115Negative regulation of microtubule polymerizationIEAbiological_process
GO:0031175Neuron projection developmentIEAbiological_process
GO:0048487Beta-tubulin bindingIEAmolecular_function
GO:0048747Muscle fiber developmentIEAbiological_process
GO:0051015Actin filament bindingIEAmolecular_function
GO:0051016Barbed-end actin filament cappingIEAbiological_process
GO:0071203WASH complexIDA IEAcellular_component
GO:0090036Regulation of protein kinase C signalingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89811029980.26417999700.99999024730.9862085779

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3256743090
GSE13712_SHEARDown-0.0925812385
GSE13712_STATICDown-0.1094209736
GSE19018Up0.1282985612
GSE19899_A1Down-0.2562309310
GSE19899_A2Up0.2037900160
PubMed_21979375_A1Down-0.1611695067
PubMed_21979375_A2Down-0.3113149970
GSE35957Up0.1174366682
GSE36640Up0.2512670321
GSE54402Up0.1392720300
GSE9593Up0.1569269250
GSE43922Down-0.0236613187
GSE24585Down-0.0452303507
GSE37065Down-0.1640059831
GSE28863_A1Up0.0958495683
GSE28863_A2Up0.0494144325
GSE28863_A3Down-0.1877845199
GSE28863_A4Down-0.2276983062
GSE48662Down-0.0044150613

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020263SequencingFunctional MTI (Weak)20371350
hsa-miR-34a-5pMIMAT0000255MIRT025479ProteomicsFunctional MTI (Weak)21566225
hsa-miR-1915-5pMIMAT0007891MIRT035771CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041682CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042833CLASHFunctional MTI (Weak)23622248
hsa-miR-3934-5pMIMAT0018349MIRT052892CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.