HCSGD entry for USP11
1. General information
| Official gene symbol | USP11 |
|---|---|
| Entrez ID | 8237 |
| Gene full name | ubiquitin specific peptidase 11 |
| Other gene symbols | UHX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004197 | Cysteine-type endopeptidase activity | TAS | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IEA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0016579 | Protein deubiquitination | IDA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3037585616 | 0.1050789408 | 0.9999902473 | 0.6213845877 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5094433639 |
| GSE13712_SHEAR | Down | -0.2347820932 |
| GSE13712_STATIC | Down | -0.1348122358 |
| GSE19018 | Down | -0.4302681204 |
| GSE19899_A1 | Down | -0.7104021009 |
| GSE19899_A2 | Down | -0.4753935271 |
| PubMed_21979375_A1 | Up | 0.5327800721 |
| PubMed_21979375_A2 | Up | 0.3177488134 |
| GSE35957 | Down | -0.9080344833 |
| GSE36640 | Down | -0.4531347570 |
| GSE54402 | Down | -0.2193691296 |
| GSE9593 | Down | -0.6074535919 |
| GSE43922 | Down | -0.3695939634 |
| GSE24585 | Up | 0.3745627347 |
| GSE37065 | Up | 0.1755119258 |
| GSE28863_A1 | Up | 0.4221769235 |
| GSE28863_A2 | Up | 0.4227842079 |
| GSE28863_A3 | Up | 0.2276975238 |
| GSE28863_A4 | Down | -0.0066978055 |
| GSE48662 | Up | 0.2444120602 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047695 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
