HCSGD entry for PNPLA4
1. General information
| Official gene symbol | PNPLA4 |
|---|---|
| Entrez ID | 8228 |
| Gene full name | patatin-like phospholipase domain containing 4 |
| Other gene symbols | DXS1283E GS2 iPLA2eta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0004806 | Triglyceride lipase activity | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9936391133 | 0.0013739296 | 0.9999902473 | 0.0715648221 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1649623837 |
| GSE13712_SHEAR | Down | -0.0073989534 |
| GSE13712_STATIC | Up | 0.1025593412 |
| GSE19018 | Down | -0.6300480541 |
| GSE19899_A1 | Down | -0.4516391227 |
| GSE19899_A2 | Down | -0.9141672963 |
| PubMed_21979375_A1 | Down | -0.5235844709 |
| PubMed_21979375_A2 | Down | -1.0026381308 |
| GSE35957 | Down | -0.0802534867 |
| GSE36640 | Down | -1.4219831573 |
| GSE54402 | Down | -0.6408121031 |
| GSE9593 | Up | 0.2841976716 |
| GSE43922 | Down | -1.1064420537 |
| GSE24585 | Down | -1.3826372213 |
| GSE37065 | Down | -0.4425435664 |
| GSE28863_A1 | Down | -0.1539463425 |
| GSE28863_A2 | Down | -0.3846690125 |
| GSE28863_A3 | Down | -0.1138664954 |
| GSE28863_A4 | Up | 0.0357438069 |
| GSE48662 | Down | -0.0838048986 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020687 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
