HCSGD entry for MIA
1. General information
| Official gene symbol | MIA |
|---|---|
| Entrez ID | 8190 |
| Gene full name | melanoma inhibitory activity |
| Other gene symbols | CD-RAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0008283 | Cell proliferation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8863306485 | 0.5579973063 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0785613642 |
| GSE13712_SHEAR | Up | 0.0405069638 |
| GSE13712_STATIC | Up | 0.2067363511 |
| GSE19018 | Down | -0.0468335818 |
| GSE19899_A1 | Down | -0.2993142590 |
| GSE19899_A2 | Up | 0.1409697531 |
| PubMed_21979375_A1 | Up | 0.0544530198 |
| PubMed_21979375_A2 | Down | -0.2046495385 |
| GSE35957 | Down | -0.2962189443 |
| GSE36640 | Up | 0.1122734359 |
| GSE54402 | Down | -0.0675318013 |
| GSE9593 | Up | 0.1247940401 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.1635911820 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23727861 | We show that ZBTB7A physically interacts with SOX9 and functionally antagonizes its transcriptional activity on key target genes such as MIA, which is involved in tumor cell invasion, and H19, a long noncoding RNA precursor for an RB-targeting microRNA |
| 23514618 | The new compounds retain high affinity to human telomeric quadruplex DNA but are 10-fold more potent against the MIA PaCa-2 pancreatic cancer cell line, with IC50 values of ~10 nM |
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