HCSGD entry for CAMK2G

1. General information

Official gene symbolCAMK2G
Entrez ID818
Gene full namecalcium/calmodulin-dependent protein kinase II gamma
Other gene symbolsCAMK CAMK-II CAMKG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleIEAbiological_process
GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0004683Calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0004723Calcium-dependent protein serine/threonine phosphatase activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEA NASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005954Calcium- and calmodulin-dependent protein kinase complexTAScellular_component
GO:0006816Calcium ion transportIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0014733Regulation of skeletal muscle adaptationTASbiological_process
GO:0016311DephosphorylationNASbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030073Insulin secretionNASbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0033017Sarcoplasmic reticulum membraneIEAcellular_component
GO:0046777Protein autophosphorylationIEAbiological_process
GO:0051924Regulation of calcium ion transportTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:1901897Regulation of relaxation of cardiac muscleIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13272973290.93697746290.73783098351.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0854391471
GSE13712_SHEARUp0.4042582171
GSE13712_STATICUp0.2910397845
GSE19018Up0.1480615645
GSE19899_A1Up0.1365550352
GSE19899_A2Up0.5331311229
PubMed_21979375_A1Down-0.1939233066
PubMed_21979375_A2Up0.3388378589
GSE35957Up0.2271446499
GSE36640Up0.5701093264
GSE54402Up0.0031096227
GSE9593Up0.2728191360
GSE43922Up0.2643529658
GSE24585Down-0.2238446501
GSE37065Down-0.1389930093
GSE28863_A1Up0.1311377645
GSE28863_A2Down-0.0225202533
GSE28863_A3Up0.0707151317
GSE28863_A4Up0.0551838215
GSE48662Down-0.0595142937

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

BosutinibDB06616 -
1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amineDB08699 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-219a-5pMIMAT0000276MIRT004446Luciferase reporter assayFunctional MTI19196972
hsa-miR-1MIMAT0000416MIRT024052Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-16-5pMIMAT0000069MIRT031976ProteomicsFunctional MTI (Weak)18668040
hsa-miR-331-3pMIMAT0000760MIRT043311CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.