HCSGD entry for TLR10

1. General information

Official gene symbolTLR10
Entrez ID81793
Gene full nametoll-like receptor 10
Other gene symbolsCD290
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002224Toll-like receptor signaling pathwayTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwayIEA TASbiological_process
GO:0004888Transmembrane signaling receptor activityIEA TASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseNASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0034146Toll-like receptor 5 signaling pathwayTASbiological_process
GO:0034166Toll-like receptor 10 signaling pathwayIEA TASbiological_process
GO:0045087Innate immune responseIEA TASbiological_process
GO:0050707Regulation of cytokine secretionIEAbiological_process
GO:0050729Positive regulation of inflammatory responseIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90440217700.38873967930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1485230161
GSE13712_SHEARDown-0.0801180806
GSE13712_STATICDown-0.1916373661
GSE19018Up0.0858603173
GSE19899_A1Up0.1431071512
GSE19899_A2Up0.0840748841
PubMed_21979375_A1Up0.2195415066
PubMed_21979375_A2Down-0.0343717284
GSE35957Up0.2967839470
GSE36640Up0.2413869039
GSE54402Down-0.1217569376
GSE9593Down-0.0818879861
GSE43922Up0.0230953736
GSE24585Up0.0023505315
GSE37065Down-0.0822100537
GSE28863_A1Down-0.3982824604
GSE28863_A2Down-0.3272110988
GSE28863_A3Up0.0542705319
GSE28863_A4Down-0.0184027991
GSE48662Down-0.0600388616

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-92a-3pMIMAT0000092MIRT049221CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.