HCSGD entry for ELL
1. General information
| Official gene symbol | ELL |
|---|---|
| Entrez ID | 8178 |
| Gene full name | elongation factor RNA polymerase II |
| Other gene symbols | C19orf17 ELL1 MEN PPP1R68 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | IEA TAS | biological_process |
| GO:0008023 | Transcription elongation factor complex | IEA | cellular_component |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0015030 | Cajal body | IEA | cellular_component |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0019902 | Phosphatase binding | IDA | molecular_function |
| GO:0032786 | Positive regulation of DNA-templated transcription, elongation | TAS | biological_process |
| GO:0050434 | Positive regulation of viral transcription | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0424173512 | 0.9916399909 | 0.4602090272 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0328714285 |
| GSE13712_SHEAR | Up | 0.1754008278 |
| GSE13712_STATIC | Up | 0.2399318948 |
| GSE19018 | Down | -0.0225470119 |
| GSE19899_A1 | Up | 0.1576770767 |
| GSE19899_A2 | Up | 0.6788684403 |
| PubMed_21979375_A1 | Up | 0.5294943167 |
| PubMed_21979375_A2 | Up | 0.6429373652 |
| GSE35957 | Up | 0.2151309729 |
| GSE36640 | Down | -0.0822288171 |
| GSE54402 | Up | 0.6090210904 |
| GSE9593 | Up | 0.0819610105 |
| GSE43922 | Up | 0.4321333973 |
| GSE24585 | Up | 0.1876867471 |
| GSE37065 | Up | 0.0671021372 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0048870932 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-769-3p | MIMAT0003887 | MIRT039101 | CLASH | Functional MTI (Weak) | 23622248 |
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