HCSGD entry for ISCA1
1. General information
| Official gene symbol | ISCA1 |
|---|---|
| Entrez ID | 81689 |
| Gene full name | iron-sulfur cluster assembly 1 homolog (S. cerevisiae) |
| Other gene symbols | HBLD2 ISA1 RP11-507D14.2 hIscA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0016226 | Iron-sulfur cluster assembly | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051536 | Iron-sulfur cluster binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0098604650 | 0.9831105505 | 0.2534543945 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1126882650 |
| GSE13712_SHEAR | Up | 0.1404285176 |
| GSE13712_STATIC | Up | 0.0350089234 |
| GSE19018 | Up | 0.2557267067 |
| GSE19899_A1 | Up | 0.7963946377 |
| GSE19899_A2 | Up | 0.8535209225 |
| PubMed_21979375_A1 | Up | 1.4641200650 |
| PubMed_21979375_A2 | Up | 0.9703541833 |
| GSE35957 | Up | 0.3525612059 |
| GSE36640 | Up | 0.1336247984 |
| GSE54402 | Up | 0.3785579082 |
| GSE9593 | Down | -0.2261888039 |
| GSE43922 | Up | 0.3363798130 |
| GSE24585 | Up | 0.2827605645 |
| GSE37065 | Down | -0.0647529325 |
| GSE28863_A1 | Up | 0.2022198282 |
| GSE28863_A2 | Up | 0.4307124238 |
| GSE28863_A3 | Up | 0.2589254623 |
| GSE28863_A4 | Up | 0.1245008797 |
| GSE48662 | Down | -0.1377315894 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181c-5p | MIMAT0000258 | MIRT047223 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
