HCSGD entry for AKAP1
1. General information
| Official gene symbol | AKAP1 |
|---|---|
| Entrez ID | 8165 |
| Gene full name | A kinase (PRKA) anchor protein 1 |
| Other gene symbols | AKAP AKAP121 AKAP149 AKAP84 D-AKAP1 PPP1R43 PRKA1 SAKAP84 TDRD17 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0982173816 | 0.7190955131 | 0.6539791804 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2105817952 |
| GSE13712_SHEAR | Up | 0.3793493660 |
| GSE13712_STATIC | Up | 0.6703511160 |
| GSE19018 | Down | -0.3515150641 |
| GSE19899_A1 | Down | -0.0995279920 |
| GSE19899_A2 | Up | 0.6549302271 |
| PubMed_21979375_A1 | Down | -0.0880056161 |
| PubMed_21979375_A2 | Up | 0.6582265384 |
| GSE35957 | Down | -0.5247875552 |
| GSE36640 | Down | -0.2943367062 |
| GSE54402 | Down | -0.1716854102 |
| GSE9593 | Up | 0.0665470705 |
| GSE43922 | Up | 0.5391095456 |
| GSE24585 | Down | -0.1370940521 |
| GSE37065 | Down | -0.0151825076 |
| GSE28863_A1 | Up | 0.1516844627 |
| GSE28863_A2 | Up | 0.2332736953 |
| GSE28863_A3 | Up | 0.3150244946 |
| GSE28863_A4 | Up | 0.0250718812 |
| GSE48662 | Down | -0.0013942364 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT005814 | Microarray | Functional MTI (Weak) | 21282569 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037317 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17081159 | In this study, we examined the role of A-kinase anchoring proteins (AKAP) in the regulation of LPA-stimulated cAMP production in senescent fibroblasts |
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