HCSGD entry for TRIM8
1. General information
| Official gene symbol | TRIM8 |
|---|---|
| Entrez ID | 81603 |
| Gene full name | tripartite motif containing 8 |
| Other gene symbols | GERP RNF27 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA NAS | molecular_function |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016605 | PML body | IDA | cellular_component |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0198241594 | 0.9886855059 | 0.3412990190 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1249872987 |
| GSE13712_SHEAR | Up | 0.9652357855 |
| GSE13712_STATIC | Up | 0.7334620977 |
| GSE19018 | Up | 0.0831629548 |
| GSE19899_A1 | Up | 0.3016327504 |
| GSE19899_A2 | Up | 1.0428043171 |
| PubMed_21979375_A1 | Up | 0.4547616140 |
| PubMed_21979375_A2 | Up | 0.5598513178 |
| GSE35957 | Up | 0.1339339225 |
| GSE36640 | Down | -0.1069241149 |
| GSE54402 | Up | 0.2640481376 |
| GSE9593 | Up | 0.1466272880 |
| GSE43922 | Up | 0.6405694621 |
| GSE24585 | Down | -0.0812851803 |
| GSE37065 | Down | -0.0001197897 |
| GSE28863_A1 | Up | 0.1605475978 |
| GSE28863_A2 | Up | 0.1583578064 |
| GSE28863_A3 | Down | -0.0240660629 |
| GSE28863_A4 | Up | 0.0157675158 |
| GSE48662 | Down | -0.0780252622 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018878 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025917 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048914 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051030 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
