HCSGD entry for SGPP1
1. General information
| Official gene symbol | SGPP1 |
|---|---|
| Entrez ID | 81537 |
| Gene full name | sphingosine-1-phosphate phosphatase 1 |
| Other gene symbols | SPPase1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006668 | Sphinganine-1-phosphate metabolic process | IEA | biological_process |
| GO:0006670 | Sphingosine metabolic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030148 | Sphingolipid biosynthetic process | TAS | biological_process |
| GO:0042392 | Sphingosine-1-phosphate phosphatase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0097191 | Extrinsic apoptotic signaling pathway | IEA | biological_process |
| GO:0097193 | Intrinsic apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6984488241 | 0.1125755898 | 0.9999902473 | 0.6428867679 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2131464168 |
| GSE13712_SHEAR | Up | 0.1964135188 |
| GSE13712_STATIC | Up | 0.3956451258 |
| GSE19018 | Down | -0.0454033390 |
| GSE19899_A1 | Down | -0.3772792662 |
| GSE19899_A2 | Down | -0.1636600454 |
| PubMed_21979375_A1 | Down | -0.2677763527 |
| PubMed_21979375_A2 | Down | -0.5439572645 |
| GSE35957 | Up | 0.3450860893 |
| GSE36640 | Up | 0.6458246174 |
| GSE54402 | Down | -0.3616866154 |
| GSE9593 | Up | 0.5201312402 |
| GSE43922 | Down | -0.0689796879 |
| GSE24585 | Up | 0.0030354112 |
| GSE37065 | Down | -0.0723101641 |
| GSE28863_A1 | Down | -0.3232220658 |
| GSE28863_A2 | Up | 0.0789552806 |
| GSE28863_A3 | Down | -0.1314319059 |
| GSE28863_A4 | Up | 0.0848313108 |
| GSE48662 | Down | -0.5172917868 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021888 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024760 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025318 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026208 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
