HCSGD entry for KCNH6

1. General information

Official gene symbolKCNH6
Entrez ID81033
Gene full namepotassium voltage-gated channel, subfamily H (eag-related), member 6
Other gene symbolsERG2 HERG2 Kv11.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004871Signal transducer activityIEAmolecular_function
GO:0005249Voltage-gated potassium channel activityIBA IEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIBAcellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0042391Regulation of membrane potentialIBAbiological_process
GO:0071805Potassium ion transmembrane transportIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31870864330.95078784240.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0572371565
GSE13712_SHEARUp0.0017184939
GSE13712_STATICUp0.1799779777
GSE19018Up0.0357270888
GSE19899_A1Up0.2075747632
GSE19899_A2Up0.2052575673
PubMed_21979375_A1Down-0.0266492147
PubMed_21979375_A2Up0.1334282017
GSE35957Up0.0002749869
GSE36640Up0.0380773084
GSE54402Up0.0583633866
GSE9593Up0.0621383320
GSE43922Up0.4735092890
GSE24585Down-0.0364375907
GSE37065Down-0.0855028439
GSE28863_A1Down-0.1088369425
GSE28863_A2Down-0.0396422139
GSE28863_A3Up0.2946569544
GSE28863_A4Up0.0974818524
GSE48662Down-0.0388343051

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IbutilideDB00308 APRD01025
PrazosinDB00457 APRD00020
MiconazoleDB01110 APRD01115
TerazosinDB01162 APRD00667

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.