HCSGD entry for TUBB1
1. General information
| Official gene symbol | TUBB1 |
|---|---|
| Entrez ID | 81027 |
| Gene full name | tubulin, beta 1 class VI |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
| GO:0051225 | Spindle assembly | IEA | biological_process |
| GO:0051258 | Protein polymerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8723975343 | 0.4840144789 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0170650203 |
| GSE13712_SHEAR | Down | -0.0022896928 |
| GSE13712_STATIC | Up | 0.1041434146 |
| GSE19018 | Down | -0.1269306219 |
| GSE19899_A1 | Up | 0.1313719527 |
| GSE19899_A2 | Down | -0.0873120390 |
| PubMed_21979375_A1 | Down | -0.0117421424 |
| PubMed_21979375_A2 | Down | -0.1654411411 |
| GSE35957 | Up | 0.0371499582 |
| GSE36640 | Down | -0.0412517346 |
| GSE54402 | Down | -0.0506052065 |
| GSE9593 | Down | -0.0688007570 |
| GSE43922 | Up | 0.0100817171 |
| GSE24585 | Down | -0.2728172224 |
| GSE37065 | Down | -0.1065937539 |
| GSE28863_A1 | Down | -0.0247325769 |
| GSE28863_A2 | Down | -0.1739294289 |
| GSE28863_A3 | Up | 0.2266103259 |
| GSE28863_A4 | Up | 0.1981330289 |
| GSE48662 | Up | 0.0198809151 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vindesine | DB00309 | APRD00392 |
| Docetaxel | DB01248 | APRD00932 |
| Colchicine | DB01394 | - |
| Epothilone D | DB01873 | EXPT01350 |
| Epothilone B | DB03010 | EXPT01349 |
| E7389 | DB04940 | - |
| CYT997 | DB05147 | - |
| ZEN-012 | DB06042 | - |
| Cabazitaxel | DB06772 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-183-5p | MIMAT0000261 | MIRT047076 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
