HCSGD entry for ALX1


1. General information

Official gene symbolALX1
Entrez ID8092
Gene full nameALX homeobox 1
Other gene symbolsCART1 FND3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001502Cartilage condensationTASbiological_process
GO:0001843Neural tube closureIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007420Brain developmentTASbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0014031Mesenchymal cell developmentIEAbiological_process
GO:0030326Embryonic limb morphogenesisIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0060021Palate developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73621893550.25416817370.99999024730.9667572977

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0998000816
GSE13712_SHEARUp0.3623388298
GSE13712_STATICUp0.1726957481
GSE19018Down-0.0550079129
GSE19899_A1Up0.1298583519
GSE19899_A2Up0.0821887689
PubMed_21979375_A1Up0.1473809218
PubMed_21979375_A2Down-0.0110157251
GSE35957Down-0.4705753719
GSE36640Up0.0641800240
GSE54402Up0.0479312381
GSE9593Down-0.3691223924
GSE43922Up0.0116557312
GSE24585Down-0.5382288626
GSE37065Down-0.0276300549
GSE28863_A1Down-0.0450073385
GSE28863_A2Down-0.1277254137
GSE28863_A3Up0.0882998839
GSE28863_A4Down-0.0261855753
GSE48662Down-0.4229162123

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029276MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.