HCSGD entry for ALX1
1. General information
Official gene symbol | ALX1 |
---|---|
Entrez ID | 8092 |
Gene full name | ALX homeobox 1 |
Other gene symbols | CART1 FND3 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
GO:0001502 | Cartilage condensation | TAS | biological_process |
GO:0001843 | Neural tube closure | IEA | biological_process |
GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005634 | Nucleus | IDA | cellular_component |
GO:0005667 | Transcription factor complex | IEA | cellular_component |
GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
GO:0007275 | Multicellular organismal development | TAS | biological_process |
GO:0007420 | Brain development | TAS | biological_process |
GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
GO:0014031 | Mesenchymal cell development | IEA | biological_process |
GO:0030326 | Embryonic limb morphogenesis | IEA | biological_process |
GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
GO:0060021 | Palate development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.7362189355 | 0.2541681737 | 0.9999902473 | 0.9667572977 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.0998000816 |
GSE13712_SHEAR | Up | 0.3623388298 |
GSE13712_STATIC | Up | 0.1726957481 |
GSE19018 | Down | -0.0550079129 |
GSE19899_A1 | Up | 0.1298583519 |
GSE19899_A2 | Up | 0.0821887689 |
PubMed_21979375_A1 | Up | 0.1473809218 |
PubMed_21979375_A2 | Down | -0.0110157251 |
GSE35957 | Down | -0.4705753719 |
GSE36640 | Up | 0.0641800240 |
GSE54402 | Up | 0.0479312381 |
GSE9593 | Down | -0.3691223924 |
GSE43922 | Up | 0.0116557312 |
GSE24585 | Down | -0.5382288626 |
GSE37065 | Down | -0.0276300549 |
GSE28863_A1 | Down | -0.0450073385 |
GSE28863_A2 | Down | -0.1277254137 |
GSE28863_A3 | Up | 0.0882998839 |
GSE28863_A4 | Down | -0.0261855753 |
GSE48662 | Down | -0.4229162123 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-26b-5p | MIMAT0000083 | MIRT029276 | Microarray | Functional MTI (Weak) | 19088304 |
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