HCSGD entry for NPL

1. General information

Official gene symbolNPL
Entrez ID80896
Gene full nameN-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
Other gene symbolsC112 C1orf13 NAL NPL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005737CytoplasmIEAcellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0008747N-acetylneuraminate lyase activityISSmolecular_function
GO:0016829Lyase activityIEAmolecular_function
GO:0019262N-acetylneuraminate catabolic processIEA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86975518410.72140275450.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0044364145
GSE13712_SHEARDown-0.1389051082
GSE13712_STATICDown-0.1915886580
GSE19018Down-0.0470073976
GSE19899_A1Up0.0501525391
GSE19899_A2Up0.1241889839
PubMed_21979375_A1Up0.1651674230
PubMed_21979375_A2Up0.2192602120
GSE35957Up0.1066263426
GSE36640Up0.0868912933
GSE54402Up0.0237192965
GSE9593Down-0.1292409029
GSE43922Up0.0186192543
GSE24585Down-0.1651955081
GSE37065Down-0.0334657959
GSE28863_A1Up0.0015677158
GSE28863_A2Up0.1009397675
GSE28863_A3Up0.0566571593
GSE28863_A4Down-0.0085363845
GSE48662Down-0.1433609812

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.