HCSGD entry for ILKAP


1. General information

Official gene symbolILKAP
Entrez ID80895
Gene full nameintegrin-linked kinase-associated serine/threonine phosphatase
Other gene symbolsILKAP2 ILKAP3 PP2C-DELTA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0004722Protein serine/threonine phosphatase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0006470Protein dephosphorylationIEAbiological_process
GO:0033262Regulation of nuclear cell cycle DNA replicationIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97732336920.02068319210.99999024730.2780737621

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1461377497
GSE13712_SHEARDown-0.0730952862
GSE13712_STATICDown-0.1466296850
GSE19018Down-0.5054018915
GSE19899_A1Down-0.6547621872
GSE19899_A2Up0.0045557144
PubMed_21979375_A1Down-0.5956858671
PubMed_21979375_A2Down-0.3978364790
GSE35957Down-0.6195587626
GSE36640Down-0.6789384616
GSE54402Up0.1949069038
GSE9593Down-0.4144274818
GSE43922Up0.0844911700
GSE24585Down-0.1895731346
GSE37065Down-0.0552103868
GSE28863_A1Down-0.0294173843
GSE28863_A2Down-0.0038993830
GSE28863_A3Down-0.5013450435
GSE28863_A4Down-0.1447725130
GSE48662Down-0.5965079484

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037443CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052596CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.