HCSGD entry for BHLHB9
1. General information
| Official gene symbol | BHLHB9 |
|---|---|
| Entrez ID | 80823 |
| Gene full name | basic helix-loop-helix domain containing, class B, 9 |
| Other gene symbols | p60TRP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9729296189 | 0.0097910832 | 0.9999902473 | 0.1959780228 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0106064455 |
| GSE13712_SHEAR | Down | -0.1981468868 |
| GSE13712_STATIC | Up | 0.2320158723 |
| GSE19018 | Up | 0.0385980617 |
| GSE19899_A1 | Down | -0.3525000931 |
| GSE19899_A2 | Down | -1.2885661548 |
| PubMed_21979375_A1 | Down | -2.0388182092 |
| PubMed_21979375_A2 | Down | -0.8982163471 |
| GSE35957 | Down | -0.6252393980 |
| GSE36640 | Down | -0.3659668588 |
| GSE54402 | Down | -0.3696106601 |
| GSE9593 | Up | 0.0167010693 |
| GSE43922 | Down | -0.8355487672 |
| GSE24585 | Down | -0.2746786131 |
| GSE37065 | Down | -0.0901135882 |
| GSE28863_A1 | Up | 0.0627706019 |
| GSE28863_A2 | Up | 0.1653185278 |
| GSE28863_A3 | Down | -0.1536599257 |
| GSE28863_A4 | Down | -0.2115079533 |
| GSE48662 | Up | 0.1435742024 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-425-5p | MIMAT0003393 | MIRT016652 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 15034937 | Characterizing the new transcription regulator protein p60TRP |
| 15034937 | Using bioinformatics-, Western-blotting-, yeast-two-hybrid-system-, polymerase chain reaction (PCR)-, and fluorescence microscopy-analyses, we demonstrate here that the neuroprotective protein p60TRP (p60-transcription-regulator-protein) is a basic helix-loop-helix (bHLH) domain-containing member of a new protein family that interacts with the Ran-binding-protein-5 (RanBP5) and the protein-phosphatase-2A (PP2A) |
| 15034937 | The additional findings of its influence on NNT1 and p48ZnF (new-neurotrophin-1, p48-zinc-finger-protein)-signaling and its down-regulation in the brain of AD subjects point to a possible pivotal role of p60TRP in the control of cellular aging and survival |
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