HCSGD entry for NDFIP1

1. General information

Official gene symbolNDFIP1
Entrez ID80762
Gene full nameNedd4 family interacting protein 1
Other gene symbolsN4WBP5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0002761Regulation of myeloid leukocyte differentiationIEAbiological_process
GO:0002829Negative regulation of type 2 immune responseIEAbiological_process
GO:0004871Signal transducer activityIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005938Cell cortexIEAcellular_component
GO:0006879Cellular iron ion homeostasisIMPbiological_process
GO:0007165Signal transductionIMPbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0010629Negative regulation of gene expressionIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0031398Positive regulation of protein ubiquitinationIMPbiological_process
GO:0032410Negative regulation of transporter activityIMPbiological_process
GO:0032713Negative regulation of interleukin-4 productionIEAbiological_process
GO:0042130Negative regulation of T cell proliferationIEAbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIMPbiological_process
GO:0043162Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathwayIEAbiological_process
GO:0045619Regulation of lymphocyte differentiationIEAbiological_process
GO:0045732Positive regulation of protein catabolic processIEAbiological_process
GO:0048294Negative regulation of isotype switching to IgE isotypesIEAbiological_process
GO:0048302Regulation of isotype switching to IgG isotypesIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0050699WW domain bindingIEAmolecular_function
GO:0050728Negative regulation of inflammatory responseIEAbiological_process
GO:0051224Negative regulation of protein transportIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27896067020.64131893930.97600354861.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1979032561
GSE13712_SHEARDown-0.0167883576
GSE13712_STATICUp0.0841014679
GSE19018Up0.2422379781
GSE19899_A1Down-0.1763579867
GSE19899_A2Up0.2520435758
PubMed_21979375_A1Down-0.6746867261
PubMed_21979375_A2Down-0.1076877345
GSE35957Up0.3278714357
GSE36640Up0.7192152811
GSE54402Down-0.4859831407
GSE9593Up0.2584216488
GSE43922Down-0.0586690712
GSE24585Up0.1351001964
GSE37065Up0.1333351142
GSE28863_A1Up0.2037049683
GSE28863_A2Up0.3195835876
GSE28863_A3Down-0.2065879723
GSE28863_A4Down-0.1757750624
GSE48662Up0.1926445637

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-221-3pMIMAT0000278MIRT024174SequencingFunctional MTI (Weak)20371350
hsa-miR-30a-5pMIMAT0000087MIRT028563ProteomicsFunctional MTI (Weak)18668040
hsa-miR-378a-3pMIMAT0000732MIRT043897CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046433CLASHFunctional MTI (Weak)23622248
hsa-miR-196a-5pMIMAT0000226MIRT048220CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.