HCSGD entry for SRCIN1

1. General information

Official gene symbolSRCIN1
Entrez ID80725
Gene full nameSRC kinase signaling inhibitor 1
Other gene symbolsP140 SNIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006887ExocytosisIEAbiological_process
GO:0007162Negative regulation of cell adhesionIEAbiological_process
GO:0014069Postsynaptic densityISScellular_component
GO:0015629Actin cytoskeletonIDAcellular_component
GO:0019901Protein kinase bindingIDAmolecular_function
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030027LamellipodiumIEAcellular_component
GO:0030175FilopodiumIEAcellular_component
GO:0030334Regulation of cell migrationIEA IMPbiological_process
GO:0030424AxonISScellular_component
GO:0030425DendriteISScellular_component
GO:0034446Substrate adhesion-dependent cell spreadingIEA IMPbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0045202SynapseISScellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0050709Negative regulation of protein secretionIEAbiological_process
GO:0061001Regulation of dendritic spine morphogenesisIEA IMPbiological_process
GO:0061098Positive regulation of protein tyrosine kinase activityIDAbiological_process
GO:0061099Negative regulation of protein tyrosine kinase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43224849360.84011099500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0789556890
GSE13712_SHEARDown-0.0155160231
GSE13712_STATICUp0.0053798987
GSE19018Up0.1321602747
GSE19899_A1Up0.1622100828
GSE19899_A2Up0.0048811232
PubMed_21979375_A1Up0.0937649869
PubMed_21979375_A2Down-0.1422224110
GSE35957Up0.1344165198
GSE36640Up0.0463386253
GSE54402Up0.0720089670
GSE9593Up0.0333992147
GSE43922Up0.0246807366
GSE24585Up0.1758999811
GSE37065Down-0.0514565838
GSE28863_A1Down-0.2766585835
GSE28863_A2Down-0.0354284840
GSE28863_A3Up0.5767689816
GSE28863_A4Up0.1282595713
GSE48662Up0.0234858769

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.