HCSGD entry for ESX1
1. General information
| Official gene symbol | ESX1 |
|---|---|
| Entrez ID | 80712 |
| Gene full name | ESX homeobox 1 |
| Other gene symbols | ESX1L ESXR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0051726 | Regulation of cell cycle | IDA | biological_process |
| GO:0060713 | Labyrinthine layer morphogenesis | IEA | biological_process |
| GO:0060716 | Labyrinthine layer blood vessel development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8281566772 | 0.5189515710 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2192334612 |
| GSE13712_SHEAR | Down | -0.0190526065 |
| GSE13712_STATIC | Up | 0.0705329611 |
| GSE19018 | Up | 0.0277637123 |
| GSE19899_A1 | Down | -0.0086350223 |
| GSE19899_A2 | Up | 0.0798368008 |
| PubMed_21979375_A1 | Down | -0.0788340967 |
| PubMed_21979375_A2 | Up | 0.0769916933 |
| GSE35957 | Up | 0.0800722007 |
| GSE36640 | Up | 0.0410689864 |
| GSE54402 | Up | 0.2945319137 |
| GSE9593 | Down | -0.0887679713 |
| GSE43922 | Up | 0.0115638150 |
| GSE24585 | Down | -0.1787502196 |
| GSE37065 | Down | -0.0751544575 |
| GSE28863_A1 | Up | 0.0128477598 |
| GSE28863_A2 | Down | -0.1709548325 |
| GSE28863_A3 | Up | 0.1887050052 |
| GSE28863_A4 | Down | -0.1085569277 |
| GSE48662 | Up | 0.0432448973 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018679 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
