HCSGD entry for PDHX
1. General information
| Official gene symbol | PDHX |
|---|---|
| Entrez ID | 8050 |
| Gene full name | pyruvate dehydrogenase complex, component X |
| Other gene symbols | DLDBP E3BP OPDX PDX1 proX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006090 | Pyruvate metabolic process | TAS | biological_process |
| GO:0010510 | Regulation of acetyl-CoA biosynthetic process from pyruvate | TAS | biological_process |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0127251396 | 0.8895265681 | 0.2819346801 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5779733320 |
| GSE13712_SHEAR | Up | 0.0933836685 |
| GSE13712_STATIC | Up | 0.3048515805 |
| GSE19018 | Down | -0.3371240653 |
| GSE19899_A1 | Up | 1.3242535553 |
| GSE19899_A2 | Up | 0.6011068759 |
| PubMed_21979375_A1 | Up | 0.7930724386 |
| PubMed_21979375_A2 | Up | 1.2318433781 |
| GSE35957 | Down | -0.1073023492 |
| GSE36640 | Up | 0.8668707520 |
| GSE54402 | Up | 0.1265501956 |
| GSE9593 | Down | -0.2545404151 |
| GSE43922 | Up | 0.5233905837 |
| GSE24585 | Up | 0.1559440112 |
| GSE37065 | Up | 0.3068414123 |
| GSE28863_A1 | Up | 0.0226702618 |
| GSE28863_A2 | Down | -0.2508682591 |
| GSE28863_A3 | Down | -0.5125654478 |
| GSE28863_A4 | Up | 0.2188998845 |
| GSE48662 | Down | -0.3454200853 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT020386 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030260 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032040 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032478 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-181d-5p | MIMAT0002821 | MIRT041176 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041546 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044791 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047246 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051324 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
