HCSGD entry for WDR61
1. General information
| Official gene symbol | WDR61 |
|---|---|
| Entrez ID | 80349 |
| Gene full name | WD repeat domain 61 |
| Other gene symbols | REC14 SKI8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0016593 | Cdc73/Paf1 complex | IDA | cellular_component |
| GO:0032968 | Positive regulation of transcription elongation from RNA polymerase II promoter | IDA | biological_process |
| GO:0035327 | Transcriptionally active chromatin | IDA | cellular_component |
| GO:0045638 | Negative regulation of myeloid cell differentiation | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0051571 | Positive regulation of histone H3-K4 methylation | IMP | biological_process |
| GO:0055087 | Ski complex | IDA | cellular_component |
| GO:0080182 | Histone H3-K4 trimethylation | IMP | biological_process |
| GO:2001162 | Positive regulation of histone H3-K79 methylation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9788978838 | 0.0928046123 | 0.9999902473 | 0.5800820988 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0327826358 |
| GSE13712_SHEAR | Down | -0.0184733152 |
| GSE13712_STATIC | Down | -0.0691556040 |
| GSE19018 | Down | -0.2612870474 |
| GSE19899_A1 | Down | -0.2558897232 |
| GSE19899_A2 | Down | -0.1161679788 |
| PubMed_21979375_A1 | Down | -0.5334725645 |
| PubMed_21979375_A2 | Down | -0.3053230672 |
| GSE35957 | Down | -0.0829520613 |
| GSE36640 | Down | -0.1137975622 |
| GSE54402 | Up | 0.0238605896 |
| GSE9593 | Down | -0.1979507759 |
| GSE43922 | Down | -0.2616521024 |
| GSE24585 | Down | -0.0754166904 |
| GSE37065 | Down | -0.0149671524 |
| GSE28863_A1 | Up | 0.1364651929 |
| GSE28863_A2 | Up | 0.0167589445 |
| GSE28863_A3 | Down | -0.4089784854 |
| GSE28863_A4 | Up | 0.1535299900 |
| GSE48662 | Down | -0.5208800546 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT024165 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036059 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051788 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
