HCSGD entry for NCOA4
1. General information
| Official gene symbol | NCOA4 |
|---|---|
| Entrez ID | 8031 |
| Gene full name | nuclear receptor coactivator 4 |
| Other gene symbols | ARA70 ELE1 PTC3 RFG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003713 | Transcription coactivator activity | NAS | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008584 | Male gonad development | TAS | biological_process |
| GO:0009725 | Response to hormone | IEA | biological_process |
| GO:0030521 | Androgen receptor signaling pathway | NAS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0050681 | Androgen receptor binding | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0754828768 | 0.9514674177 | 0.5819026354 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3409924749 |
| GSE13712_SHEAR | Up | 0.3697994478 |
| GSE13712_STATIC | Up | 0.7094863133 |
| GSE19018 | Down | -0.4837854950 |
| GSE19899_A1 | Up | 0.0492258719 |
| GSE19899_A2 | Up | 0.2329778666 |
| PubMed_21979375_A1 | Down | -0.0379432583 |
| PubMed_21979375_A2 | Up | 0.6166140339 |
| GSE35957 | Up | 0.1815874452 |
| GSE36640 | Up | 0.5064692270 |
| GSE54402 | Up | 0.0396654180 |
| GSE9593 | Up | 0.0256506291 |
| GSE43922 | Up | 0.0445827922 |
| GSE24585 | Up | 0.0401335159 |
| GSE37065 | Down | -0.0892356192 |
| GSE28863_A1 | Up | 0.0299273633 |
| GSE28863_A2 | Up | 0.1341434050 |
| GSE28863_A3 | Up | 0.1787205134 |
| GSE28863_A4 | Up | 0.0767931550 |
| GSE48662 | Up | 0.2359742372 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038845 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041830 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-365a-3p | MIMAT0000710 | MIRT044019 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
